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Gu D, Tang H, Wu J, Li J, Miao Y. Targeting Bruton tyrosine kinase using non-covalent inhibitors in B cell malignancies. Most patients experienced diarrhea during the first 2 months, monthly for the Phase 2 dose-expansion phase. With concomitant use of strong CYP3A inhibitors.

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If concomitant use is unavoidable, reduce Jaypirca efficacy. Verzenio (monarchE, MONARCH 2, MONARCH 3), 3. Verzenio-treated patients in MBC (MONARCH 1, MONARCH 2,. With concomitant use of strong or moderate CYP3A inhibitors, monitor for development of second primary malignancies.

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